Ketamine is used as an anesthetic for surgery, a treatment for depression, and is a drug of abuse. Ketamine is FDA-approved as an anesthetic to put you to sleep for surgery and to help prevent pain and discomfort. Ketamine for depression is an off-label use, and its use for depression is currently being researched in clinical trials. It is also a drug of abuse that is used illegally recreationally for its hallucinogenic properties and is known to be a “date rape” drug as it causes short-term memory loss.
Ketamine is not an opioid (narcotic); it is an NMDA receptor antagonist, which means it blocks the N-methyl-D-aspartate (NMDA) neurotransmitter in the brain.
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